Springs Rejuvenation, a physician-led regenerative medicine practice, has expanded its proprietary Stem 3 Protocol to all five of its United States locations, making exosome-based hair restoration available in New York City, Los Angeles, Austin, Miami, and Atlanta. The expansion eliminates the need for patients to travel abroad for advanced hair restoration treatments.
The Stem 3 Protocol combines three components: peptide therapy, exosome hair treatment, and micro follicular unit extraction (micro FUE) using 0.9mm instrumentation. This smaller incision diameter, compared to conventional FUE punches ranging from 1.0mm to 1.5mm, is designed to minimize scalp trauma and support faster recovery. Exosomes, extracellular vesicles derived from stem cells, deliver signaling proteins and growth factors to hair follicle cells, priming the scalp before and after the micro FUE procedure to extend the active growth phase of the hair cycle and reinforce follicle density. Peptide therapy is administered as a preparatory measure to optimize cellular conditions.
Until recently, patients seeking non-surgical hair restoration with exosomes often traveled to clinics in Europe, Mexico, or Southeast Asia due to more permissive regulatory frameworks. Springs Rejuvenation's multi-city expansion positions it as one of the few domestic providers offering this combination protocol at scale across multiple states. Dr. Charles Pereyra, MD, Medical Director of Springs Rejuvenation, stated, 'With five active clinic locations, we have now treated patients in every major US time zone under the Stem 3 Protocol. Our 0.9mm micro FUE instrumentation paired with exosome hair treatment means patients are no longer choosing between quality and convenience—they can access this level of care in their home city.'
Each clinic operates under direct physician supervision, and the practice also offers stem cell exosome therapy for joint conditions, making them integrated regenerative medicine centers. Hair restoration without surgery is an increasingly documented area, with research examining exosome signaling in dermal papilla cells. Springs Rejuvenation applies this science within a structured clinical framework, including an intake assessment before initiating the Stem 3 Protocol. For more information, visit Springs Rejuvenation.


